September 5, 2012

Male Birth Control Pill Around The Corner

Attention men: The day may be coming soon when you can take your own birth control pill with no side effects, according to a study done by a group of scientists that includes a Texas A&M University researcher.

Qinglei Li

Qinglei Li

Qinglei Li, an assistant professor in Texas A&M’s College of Veterinary Medicine & Biomedical Sciences, is part of a team of researchers led by Martin Matzuk at Baylor College of Medicine and James Bradner at Dana-Farber Cancer Institute who made the discovery, and their work is published in the journal Cell.

Working on mice, the team found that a compound called JQ1 acts as an inhibitor to sperm production and also sperm mobility.

“Both of these are needed for fertility, but JQ1 prevents both,” Li says of the findings.

“It stopped the sperm production very dramatically. More good news is that there appear to be no side effects whatsoever. Once the JQ1 was no longer given to the mice, they were back to their normal reproduction rates, and it did not affect mating behavior or the health of the offspring.”

Though the mice were given injections, the team believes that a pill could eventually be developed for the same results.

A male contraceptive pill has been talked about for decades, but so far none has been successfully created despite a strong demand.

While many men might be reluctant to take out the trash or ask for directions if they are lost, recent studies have shown that about 70 percent of men would be willing to take a birth control pill if it were available.

New compound halts male reproduction

One drawback to many female contraceptives is that they sometimes interfere with hormones, especially estrogen. But Li says the team is confident that JQ1 does not affect testosterone levels in men, and appears to have no other side effects as well.

As with many discoveries, the JQ1 compound appears to have come about by accident.

It was originally used for anti-cancer treatments, but researchers found it was also an excellent compound in controlling fertility.

“This is an exciting step in male contraception,” Li adds.

“A compound with more specificity will be needed before clinical trials can be done for humans. It does not mean a male birth control just yet, but it is a great step forward in that direction.”

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Media contact: Keith Randall, News & Information Services, at (979) 845-4644 or Qinglei Li at (979) 862-2009

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5 Comments to Male Birth Control Pill Around The Corner

  1. “While many men might be reluctant to take out the trash or ask for directions if they are lost, recent studies have shown that about 70 percent of men would be willing to take a birth control pill if it were available.”

    Aaaahhh gender based humor is always funny.

  2. Ryan Brady on September 11th, 2012
  3. So. Many. Jokes. But seriously, this is a pretty cool new development, especially if there are indeed no side effects.

  4. Alistair Hughes on September 12th, 2012
  5. “Makes more sense to unload the gun than to shoot a bullet-proof vest!” haha

  6. Lauren on September 12th, 2012
  7. No such thing as “no side effects”

  8. Susan Billups on September 13th, 2012
  9. Doesn’t the introduction of mail contraceptive increase the spread of STDs in males due to the expected decline in demand for condoms as a form of contraceptive?

  10. Craig Elkins on September 13th, 2012